Abstract #3600

Quantification of 3D Cardiac Motion in Mice Using Multi-Phase DENSE MRI

Yong Chen^1,2, Jia Zhong^1,2, Xin Yu^1,2

¹Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, United States; ²Case Center for Imaging Research, Case Western Reserve University, Cleveland, OH, United States

In the current study, we developed a multi-phase DENSE imaging method for quantification of 3D myocardial motion in mice. Only five acquisitions were required to quantify both in-plane and longitudinal displacements on one slice. The results showed strong agreement with 2D DENSE methods.