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Abstract #3639

Black-Blood Preparation Improves Accuracy in Murine Phase-Contrast Cine MRI at Ultra-High Mag-Netic Fields

Erica Dall'Armellina1, Bernd Jung2, Hannah Barnes3, Stefan Neubauer1, Michael Markl2, Jurgen E. Schneider1

1Cardiovascular Medicine, University of Oxford, Oxford, Oxon, United Kingdom; 2Diagnostic Radiology, Medical Physics, University Hospital Freiburg, Freiburg, Germany; 3University of Oxford, Cardiovascular Medicine, Oxford, Oxon, United Kingdom

Tissue Phase Mapping (TPM) is a well-established technique to assess regional cardiac function in humans and in animal models such as mice. While TPM-studies in humans required suppression of the dominant blood signal in order to provide an accurate measurement of myocardial velocities, the murine studies were conducted without blood suppression. We show that bright-blood contrast can impact on both, absolute velocities and motion pattern, which can potentially and erroneously be identified as a local impairment of cardiac function.