Tobias Breyer1,2, Oliver Kraff1,2,
Stefan Maderwald1,2, Andreas Bitz1,2, Stephan Orzada1,2,
Mark E. Ladd1,2, Elke R. Gizewski1,2, Harald H. Quick,
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1Institute of Diagnostic and
Interventional Radiology and Neuroradiology, University Hospital Essen,
Essen, Nordrhein-Westfalen, Germany; 2Erwin L. Hahn Institute for
Magnetic Resonance Imaging, University of Duisburg-Essen, Essen, Germany; 3Institute
of Medical Physics, Friedrich-Alexander-University Erlangen-Nrnberg,
Erlangen, Germany
Atherosclerosis
is one leading cause of morbidity. In this study we implemented and adapted a
plaque imaging protocol from 1.5 to 7 Tesla with use of a custom-built
eight-channel transmit/receive RF array for the first time in human patients
with hemodynamically relevant atherosclerosis. This approach allows for MR
angiographic imaging without administration of gadolinium contrast comparable
to contrast-enhanced MR angiography at lower field strengths. Plaque imaging
at 7 Tesla requires different sequences compared to lower field strengths but
allows a qualitatively comparable depiction of different intraplaque components,
calcifications, vessel wall thickness and the luminal surface compared to
lower field strenghts.
Keywords