Thanh D. Nguyen1, Keigo Kawaji2, Pascal Spincemaille1, Martin R. Prince1, Yi Wang1,2
1Radiology, Weill Cornell Medical College, New York, NY, United States; 2Biomedical Engineering, Cornell University, Ithaca, NY, United States
Black blood (BB) MRI can be used to characterize vessel wall and quantify atheresclerotic plaque burden in patients with peripheral vascular disease. T2prep inversion recovery (T2IR) has been shown to provide flow-insensitive BB contrast for 2D peripheral vessel wall MRI at 1.5T at the cost of reduced wall SNR The aim of this study is to achieve a considerable increase in T2IR BB imaging efficiency to obtain large field-of-view bilateral peripheral coverage with sub-millimeter isotropic resolution in reasonable scan time using SNR-efficient volumetric 3D fast spin echo acquisition at 3T. The developed sequence was capable of providing large volumetric coverage, excellent arterial and venous blood suppression and fat suppression, as well as good vessel wall visualization in healthy volunteers.