Thanh D. Nguyen1, Keigo Kawaji2,
Pascal Spincemaille1, Martin R. Prince1, Yi Wang1,2
1Radiology, Weill Cornell Medical
College, New York, NY, United States; 2Biomedical Engineering,
Cornell University, Ithaca, NY, United States
Black
blood (BB) MRI can be used to characterize vessel wall and quantify
atheresclerotic plaque burden in patients with peripheral vascular disease.
T2prep inversion recovery (T2IR) has been shown to provide flow-insensitive
BB contrast for 2D peripheral vessel wall MRI at 1.5T at the cost of reduced
wall SNR The aim of this study is to achieve a considerable increase in T2IR
BB imaging efficiency to obtain large field-of-view bilateral peripheral
coverage with sub-millimeter isotropic resolution in reasonable scan time
using SNR-efficient volumetric 3D fast spin echo acquisition at 3T. The
developed sequence was capable of providing large volumetric coverage,
excellent arterial and venous blood suppression and fat suppression, as well
as good vessel wall visualization in healthy volunteers.
Keywords