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Abstract #3712

Investigation of Myocardium Structure of Postinfarct Porcine Model Using Superquadric Glyphs

Yin Wu1,2, Ed Xuekui Wu2,3

1Institute of Biomedical and Health Engineering, Shenzhen Institute of Advanced Technology, Shenzhen, Guangdong, China; 2Laboratory of Biomedical Imaging and Signal Processing, The University of Hong Kong, Pokfulam, Hong Kong; 3Dept. of Electrical and Electronic Engineering, The University of Hong Kong, Pokfulam, Hong Kong


Previous DTI studies on infarcted LV myocardium structure usually explored myocardial fiber orientation, diffusivity or diffusion anisotropies. In current study, superquadric glyphs were applied on infarcted porcine model. Diffusion tensor shape and laminar sheet structure were examined for the first time to describe infarcted myocardium structural alteration. Results show that significant change of diffusion tensor shape occurred in both infarct and adjacent regions. Apparent alteration of laminar sheet structure was observed in adjacent and remote regions. The current study demonstrates the ability of superquadric glyphs to detect myocardium structural degeneration and provides supplemental information for infarcted heart remodeling.

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