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Abstract #3720

4D Right Ventricular Strain in Pulmonary Hypertension and Normals

Bharath Ambale Venkatesh1, Steven G. Lloyd2, Mustafa I. Ahmed2, Himanshu Gupta2, Louid Dell'Italia2, Thomas S. Denney Jr. 1

1Electrical and Computer Engineering, Auburn University, Auburn, AL, United States; 2University of Alabama at Birmingham

Accurate assessment of right ventricular (RV) function is clinically important particularly in patients with pulmonary hypertension (PHTN). Compared to the left ventricle (LV), however, analysis of RV function is relatively difficult because of relatively thin walls and lack of geometric symmetry. Also in PHTN, higher systolic blood pressure in the RV can cause excursion of the interventricular septum into the LV cavity causing it to lose its geometric symmetry. This abstract presents a method for reconstructing three-dimensional biventricular strain from tagged MRI in each imaged time frame through mid-diastole. This method is validated on normal volunteers and PHTN patients.