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Abstract #3743

Optimization of Ultrashort TE Imaging for Angiography and Molecular Imaging of Iron-Oxide Nanoparticles

Ravi Teja Seethamraju1, Sonia Nielles-Vallespin2, Shuning Huang3, David E. Sosnovik3,4

1MR R and D, Siemens Medical Solutions, USA Inc., Charlestown, MA, United States; 2Cardiovascular MR, Royal Brompton Hospital, London, United Kingdom; 3Radiology, Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA, United States; 4Center for Molecular Imaging Research, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States

Iron oxide based USPIOs inherently exhibit T1 shortening apart from their traditional T2 properties. This property is best utilized at ultrashort echo times. We demonstrate how a single UTE sequence can produce both angiographic images as well as molecular quantitation.