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Abstract #3747

In Vivo SWIFT Imaging of SPIO Labeled Stem Cells Grafted in the Heart

Rong Zhou1, Djaudat Idiadilitum2, Curt Corum2, Hualei Zhang1, Jia Zhong1, Hui Qiao1, Steen Moeller2, Michael Garwood2

1Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States; 2Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States

We demonstrate the first in vivo cardiac image by ECG-gated SWeep Imaging with Fourier Transformation (SWIFT). Myocardium anatomies are well-visualized on 3D SWIFT magnitude images. The positive contrast on SWIFT imaginary image facilitates the detection of SPIO-containing cells while the magnitude image provides anatomical reference without requirement for additional reference image. These data suggest that SWIFT might be an alternative to currently available positive contrast methods, attractive especially in cardiovascular applications.