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Abstract #3979

MRI of Acute (<6 Hours) Ischemic Stroke Patients: A Comparison Between Diffusion-Related Parameters

Frank Peeters1, Dennis Rommel1, Andre Peeters2, Cecile Grandin1, Guy Cosnard1, Thierry Duprez1

1Medical Imaging, Universit Catholique de Louvain, Brussels, Belgium; 2Neurology, Universit Catholique de Louvain, Brussels, Belgium

The value of PW- and DW-related parameters for accurately predicting the ischemic penumbra at initial MR work-up in hyperacute stroke patients has remained probabilistic. In the frame we compared parameters obtained from DTI (2-points ADC, mono- and bi-exponential fits) and q-space imaging (tensor analysis) in a short preliminary cohort of seven hyperacute (<6 mours) stroke patients. Initial data analysis enhanced the value of using high b-values for stroke work-up. Anisotropic diffusion and QSI analysis added significantly to standard isotropic DWI and may have the potential to discriminate between worsening vs regressive infarction, and to delineate ischemic penumbra at admission work-up.