Jian Zhang1,2, Joshua Chua3,
Chunlei Liu4, Shangping Feng1, Michael Moseley2
1Department of Electrical Engineering,
Stanford University, Stanford, CA, United States; 2Department of
Radiology, Stanford University, Stanford, CA, United States; 3Department
of Neurosurgery, Stanford University, Stanford, CA, United States; 4Brain
Imaging and Analysis Center, Duke University Medical Center, Durham, NC,
United States
Animal
stroke studies with DWI are widely investigated to facilitate the development
of stroke diagnosis. However, diffusion imaging on small animals at high fields
is usually very challenging due to the resolution-SNR tradeoff and hardware
imperfection. The widely used single shot EPI DWI technique is particularly
vulnerable to these factors and tends to produce severe image artifacts. In
this work, we demonstrate the implementation of the self-navigated
interleaved spirals (SNAILS) technique on our 7T animal scanner. High quality
DWI images can be acquired for stroke studies on rats. The preliminary
diffusion tensor imaging (DTI) results are also presented.
Keywords