Matthew George Liptrot1, Tim Bjrn Dyrby1
1Danish Research Centre for Magnetic
Resonance (DRCMR), Copenhagen University Hospital, Hvidovre, Copenhagen,
Denmark
In
probabilistic streamline tractography, the choice of the number of
streamlines to employ is the source of much confusion as no feasible
analytical solution exists, and ensuring sufficient sampling is therefore
problematic. Herein we describe an investigation into the influence that the
number of streamlines imposes upon free-tracking, compare the parameters
effect within Anatomical Connectivity Map generation and show how, via use of
the ICE-T Framework (a recent technique to iterate conventional tractography
routines), as few as 10 streamlines per voxel can be sufficient to overcome
the omnipresent problem of path length dependency.
Keywords