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Abstract #4088

Design and Testing of a Phantom for Calibration of MRI Systems Used in DCE-MRI Clinical Trials

Michael H. Buonocore1, David H. Gultekin2, Michael A. Jacobs3, Steffen Sammet4, Natarajan Raghunand5, Joshua Levy6, Michael V. Knopp4

1Radiology, UC Davis Imaging Research Center, Sacramento, CA, United States; 2Memorial Sloan-Kettering Cancer Center, New York, NY, United States; 3Radiology, Johns Hopkins University, Baltimore, MD, United States; 4Radiology, Ohio State University, Columbus, OH, United States; 5Radiology, University of Arizona, Tucson, AZ, United States; 6The Phantom Laboratory, Inc., Salem, NY, United States

This study presents a new DCE-MRI phantom designed for calibration of MRI systems to be used in multi-site clinical trials. Preliminary results at four clinical sites show the ability of the phantom to reveal critical similarities but also expected and unexpected differences in the images and derived DCE-MRI parameters.