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Abstract #4296

Prognostic Value of Minimum Apparent Diffusion Coefficient for Patients with Hypopharyngeal Cancer

Yu-Chun Lin1,2, Su-Hang Ng1, Yau-Yau Wai1, You-Hsuan Tsai3, Jiun-Jie Wang3

1Department of Diagnostic Radiology, ChangGung Memorial Hospital, KweiShan, Taoyuan, Taiwan; 2Department of Electrical Engineering, ChangGung University, KweiShan, Taoyuan, Taiwan; 3Department of Medical Imaging and Radiological Science, ChangGung University, KweiShan, Taoyuan, Taiwan

The minimum ADC reflects the highest cellularity within the tumor. In this study we proposed to assess the survival rates for patients with hypopharyngeal cancer using minimum ADC, mean ADC and the tumor volume, which is the conventional standard. The Kaplan-Meier survival analysis revealed that the minimum ADC can successfully predict the 16-month overall survival with a optimal threshold of 6.9410-3 mm2/sec. Thus, the minimum ADC could serve as a biomarker for the prognosis in patients with hypopharyngeal cancer.