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Abstract #4308

The Effects of Age, Gender and BMI on Parotid Fat and Parotid ADC Measurements in EPI Based and FSE-PROPELLER Based Diffusion Weighted Imaging

Hui-Chu Chiu1,2, Chun-Jung Juan3, Hing-Chiu Chang4,5, Hsiao-Wen Chung3,5, Cheng-Chieh Cheng3,5, Su-Chin Chiu3,5, Cheng-Yi Cheng1, Cheng-Yu Chen3, Guo-Shu Huang3

1Department of Nuclear Medicine, Tri-Service General Hospital, Taipei, Taiwan; 2EMBA in Global Chinese Management, Department of Business Administration, College of Management, Tamkang University, Taipei, Taiwan; 3Department of Radiology, Tri-Service General Hospital, Taipei, Taiwan; 4Applied Science Laboratory, GE Healthcare Taiwan, Taipei, Taiwan; 5Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan

The effects of age, gender and body mass index (BMI) on parotid fat content and parotid ADC measurements have never been investigated yet. In this study, we measured parotid ADC values using non-fat-saturated and fat-saturated DWI pulse sequences including fast spin-echo PROPELLER and echoplanar acquisitions. Our results highlight the parotid fat content is influenced by gender and is significantly positively associated with age and BMI. The parotid fat content has a significantly negative effect on parotid ADC values that is most apparent in non-fat-saturated DWI pulse sequence and the effect could not be remedied by any fat-saturated DWI pulse sequence.