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Abstract #4326

Deep Gray Matter Atrophy in a Large Sample of Clinically Isolated Syndrome and Early Relapsing-Remitting Multiple Sclerosis Patients

Niels Bergsland1, Michael G. Dwyer1, Dana Horakova2, Ondrej Dolezal1, Zdenek Seidl3, Manuela Vaneckova3, Eva Havrdova2, Robert Zivadinov4

1University at Buffalo, Buffalo Neuroimaging Analysis Center, Buffalo, NY, United States; 2Charles University, Department of Neurology, Prague, Czech Republic; 3Charles University, Department of Radiology, Prague, Czech Republic; 4Neurology, Buffalo Neuroimaging Analysis Center, Buffalo , NY , United States

To quantify deep gray matter (DGM) atrophy in a large sample of clinically isolated syndrome (CIS) patients, early relapsing-remitting (RR) multiple sclerosis (MS) patients, and healthy controls (HC). To investigate the relationship between DGM atrophy and disability in CIS patients.