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Abstract #4386

Age Norms for Diffusion Tensor Data - Evaluation with TBSS

Nancy Rollins1,2, Paul Glasier3, Leanne Tamm4, Linda Butwell, Jonathan Chia5, Michael Morriss, Zhiyue Jerry Wang

1Radiology, Childrens Medical Center, Dallas, TX, United States; 2University Texas Southwestern Medical Center, Dallas, TX, United States; 3Psychiatry,, Dallas, TX, United States; 4Psychiatry, University Texas Southwestern Medical Center; 5Philips HealthCare Systems

Using TBSS, variable age effects on tensor metrics are seen across the brain in school-aged children suggesting valid comparisons of FA and diffusivities between typically developing children and children with neuro developmental or psychiatric conditions probably require age-matched cohorts unless the affects of the disease are known to be large in comparison to the scale of age effects.