Jens
H. Jensen1, Maria F. Falangola1,2, Caixia Hu1,
Ali Tabesh1, Calvin Lo1, Otto Rapalino1,3,
Joseph A. Helpern1,2
1Radiology, New York University School of
Medicine, New York, NY, United States; 2Center for Advanced Brain
Imaging, Nathan S. Kline Institute, Orangeburg, NY, United States; 3Department
of Radiology, Massachusetts General Hospital, Boston, MA, United States
Diffusional
kurtosis imaging was applied to measure the axial and radial diffusional
kurtoses for three patients with subacute focal ischemic stroke. For all
three patients, the axial diffusional kurtoses increased substantially in the
affected regions (relative to the contralateral side), but for two of the
subjects, the radial diffusional kurtoses showed little change. In these two
cases, the affected regions appeared to be primarily in white matter,
suggesting that for white matter ischemia mainly alters the diffusional
kurtosis in the axial direction.