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Abstract #4424

Implementing VERSE for Time of Flight RF Pulses at 7Tesla: Methodological Considerations

Sebastian Schmitter1, Soeren Johst2, Michael Bock2, Kamil Ugurbil1, Pierre-Francois van de Moortele1

1University of Minnesota, Center for Magnetic Resonance Research, Minneapolis, MN, United States; 2German Cancer Research Center, Heidelberg, Germany

It has been shown that successful Time-of-flight (TOF) images can be obtained at 7T benefiting from higher SNR and longer tissue T1. However, because of SAR constraints, magnetization transfer pulses that are used at 1.5T/3T cannot be used at 7T, saturation pulses are often skipped and the flipangle is limited. These issues can be addressed using the VERSE principle to decrease SAR. However, VERSE pulses are more sensitive to δB0. Here, we investigate in simulations and in vivo the impact of off-resonance frequencies on RF excitation profile of ramp shaped RF pulses (TONE) when applying VERSE at 7T.