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Abstract #4446

Imaging at 7T Reveals New Septated Fine Structure in the Human Corpus Callosum

Chris Wiggins1, Andreas Schaefer2, Bibek Dhital2, Denis Le Bihan1, Robert Turner2

1CEA NeuroSpin, Gif-sur-Yvette, France; 2Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany

At 7 T, high resolution structural imaging shows fine details of brain structures in vivo. Examining such images of the adult human corpus callosum, we have discovered two-dimensional planar structures never previously described with traditional histological techniques. Analysis of good quality DTI data at 3T supports this observation, showing a second preferred direction of water diffusion. Interhemispheric axonal connections show detailed laminar ordering at submillimeter scale.