April M. Chow1,2, Iris Y. Zhou1,2,
Shu Juan Fan1,2, Kannie W.Y. Chan1,2, Kevin C. Chan1,2,
Ed X. Wu1,2
1Laboratory of Biomedical Imaging and
Signal Processing, The University of Hong Kong, Pokfulam, Hong Kong SAR,
China; 2Department of Electrical and Electronic Engineering, The
University of Hong Kong, Pokfulam, Hong Kong SAR, China
Neonatal
monocular enucleation has been used to study developmental mechanisms
underlying visual perception and the cross-modal changes in the central
nervous system caused by early loss of the visual input. In this study, we
demonstrated that alteration in the metabolism of taurine in visual cortex
accompanied with neonatal monocular enucleation could be monitored using 1H
MRS at 7 T. The change in taurine signal with respect to creatine signal may
possibly due to the increased taurine signal in the right control visual
cortex, likely caused by the plasticity resulted from recruitment of
resources to the remaining left eye for adaptation.