Mark Ingram1, Toni Wallace2,
Erica Scurr2, David J. Collins2,3, Val Lewington4,
Dow-Mu Koh2
1Department of Radiology, St George's
Healthcare NHS Trust, Tooting, London, United Kingdom; 2Department
of Radiology, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United
Kingdom; 3CRUK-EPSRC Cancer Imaging Centre, Institute of Cancer
Research, Sutton, Surrey, United Kingdom; 4Department of Nuclear
Medicine, Royal Marsden NHS Foundation Trust, Sutton, Surrey, United Kingdom
In
patients with neuroendocrine liver metastases, imaging determination of the
size and distribution of metastatic disease is of value as it could influence
the choice of therapy. We compared diffusion-weighted MR imaging (DW-MRI) and
gadolinium-DTPA enhanced MR imaging for the detection of focal liver lesions
in patients with suspected liver metastases arising from neuroendocrine
tumours. DW-MRI was found to have a significantly higher diagnostic
sensitivity (88%) compared with gadolinium-DTPA enhanced MR imaging (77%) for
lesion detection in this patient population (p = 0.001, McNemar test).
Keywords