Stephanie M. George1, Diego R. Martin2,
Don P. Giddens1
1Wallace H. Coulter Department of
Biomedical Engineering, Georgia Institute of Technology and Emory University,
Atlanta, GA, United States; 2Department of Radiology, Emory
University School of Medicine, Atlanta, GA, United States
With
the incidence of chronic liver disease (CLD) increasing the need for improved
diagnostic measurements has increased.
Magnetic resonance imaging (MRI) and phase-contrast MR offer
noninvasive techniques which provide both high quality anatomical and
hemodynamic data. The use of these
data coupled with computational fluid dynamics (CFD) to provide detailed flow
field information is a novel approach.
This study examines a small number of normal subjects and patients
comparing PC-MR measured portal venous hemodynamic parameters including
velocity and flow rate and computational results. This work demonstrates the feasibility of
coupling MRI and CFD to investigate the altered hemodynamics in CLD.