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Abstract #4593

Gd-EOB-DTPA Combined with Gd-DTPA: Hepatobiliary Contrast with Familiar Hepatic Dynamic Contrast Enhancement

Jesse L. Wei1,2, Kimiknu Mentore1, Martin P. Smith1,2, Neil M. Rofsky1,2

1Radiology, Beth Israel Deaconess Medical Center, Boston, MA, United States; 2Harvard Medical School, Boston, MA, United States

Administration of Gd-EOB-DTPA using the recommended dose for hepatobiliary imaging results in an unfamiliar "washed out" appearance of the liver on dynamic contrast enhanced (DCE) imaging. This likely results from increased background hepatic enhancement due to early hepatobiliary uptake. Injection of a combination of Gd-EOB-DTPA in conjunction with an extracellular contrast agent provides the 20-minute delayed hepatobiliary phase, while preserving the familiar vascular contrast and lesion conspicuity compared to background liver on DCE images.