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Abstract #4595

In Vivo 1H MRS of Gallbladder Bile Using an Optimized 8-Channel Phased Array at 3T: Towards Improved Diagnosis of Hepatopancreatobiliary Diseases

Sanaz Mohajeri1,2, Tedros Bezabeh1, Scott B. King1, Omkar B. Ijare1, Gerald Y. Minuk3, Jeremy Lipschitz4, Ian C.P. Smith1

1National Research Council Institute for Biodiagnostics, Winnipeg, Manitoba, Canada; 2Human Anatomy and Cell Science, University of Manitoba, Winnipeg, Manitoba, Canada; 3Hepatology, University of Manitoba, Winnipeg, Manitoba, Canada; 4Surgery, University of Manitoba, Winnipeg, Manitoba, Canada

Considering the key role of liver in body metabolism, the study of bile composition is of great importance. In vitro 1H MRS of bile samples have shown diagnostic value in detecting various hepatopancreatobiliary disorders. Given the invasive nature of this procedure, we considered the possibility of gathering in vivo data. We present here our initial efforts to obtain bile spectra from pigs using a 3T clinical scanner comparing the use of a Siemens body array coil with an optimized home-built receive array coil.