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Abstract #4609

Ultra-Short Echo Time (UTE) MR Imaging of the Lung: Assessment of Tissue Density in the Lung Parenchyma

Masaya Takahashi1, Osamu Togao1, Riki Tsuji1, Ivan Dimitrov1

1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States

The utility of ultra-short TE (UTE) imaging in conjunction with projection acquisition of the free induction decay helps to acquire the MR signal from the lung parenchyma. We applied an UTE sequence for imaging of the murine lung at different positive end-expiratory pressures (PEEP) in a 3 T clinical MRI system. The signal intensity and T2* of the lung parenchyma measured with a UTE sequence reduced as the PEEP became higher where the lung volume increased. We found that both are highly correlated with the lung volume.