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Abstract #4613

Sensitivity of Viscosity and Elasticity in Preserved Pig Lung by Magnetic Resonance Elastography

Roberta Santarelli1, Xavier Matre1, Ralph Sinkus2, Luc Darrasse1

1Imagerie par Rsonance Magntique et MultiModalits (UMR8081), Univ Paris-Sud, CNRS, Orsay, France; 2Institut Langevin (UMR 7587), ESPCI, Univ Denis Diderot, CNRS, Paris, France

Viscoelastic properties of lungs participate in the organ basic function. Their exploration in vivo is not attainable. Hyperpolarised helium-3 MR-elastography on lungs has been demonstrated in vivo. This new technique ex vivo quantitatively evaluated the comparison between helium-3 and hydrogen MRE: the fluid/structure coupling was found to be strong, validating helium-3 lung MRE as a consistent tool for lung exploration. This work focuses on viscoelastic properties behaviour of hydrogen MRE, applied on the preserved pig lung inflated at different volumes: performance of wavelength, elasticity, and viscosity distribution is discernible throughout the inner area and the outer peripheries of the lungs