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Abstract #4622

Dynamic Contrast Enhanced Pulmonary Perfusion with Undersampled Stack-Of-Stars and Iterative Highly Constrained Back-Projection

Nathan S. Artz1, Rafael L. O'Halloran2, Mark Schiebler3, James H. Holmes4, Sean B. Fain1,3

1Medical Physics, University of Wisconsin-Madison, Madison, WI, United States; 2Radiology, Stanford University, Stanford, CA, United States; 3Radiology, University of Wisconsin-Madison, Madison, WI, United States; 4Applied Science Laboratory, GE Healthcare, Madison, WI, United States

Pulmonary perfusion was assessed in two healthy volunteers using a contrast-enhanced 3D stack-of-stars GRE sequence. Consecutive groups of 32 projection angles were reconstructed with IHYPR for a temporal resolution of ~1s. The signal vs. time curves demonstrate an expected trend with the pulmonary artery peaking first, followed next by the parenchyma and later the left atrium. Mean transit time, relative pulmonary blood volume and relative pulmonary blood flow maps demonstrate expected results with mean transit times from 3-5 s after the main pulmonary artery trunk and shorter MTTs in the posterior region due to gravity related effects.