Antonella Meloni1, Antongiulio Luciani2, Alessia Pepe1, Vincenzo Positano1, Gennaro Restaino3, Maria Chiara Dell'Amico1, Brunella Favilli1, Gianna Alberini1, Giovanni Palazzi4, Massimo Lombardi1
1MRI Lab, G. Monasterio Foundation and Institute of Clinical Physiology, CNR, Pisa, Italy; 2Istituto di Radiologia Az. Osp. "Garibaldi", Catania, Italy; 3Catholic University, Campobasso, Italy; 4Policlinico di Modena, Modena, Italy
The goals of our study were to set up a MRI acquisition technique for the detection of the iron burden in the whole liver of thalassemia major patients. Significant differences in the segmental T2* values were found. Specifically, the mean T2* values over the segments VI and VIII were significantly lower than the mean T2* values over the other segments. However, T2* variations in liver are low and likely due to the artefacts effects and measurement variability.