Ran-Chou Chen1,2, Chen-Te Chou3,4
1Biomedical Imaging and Radiological Science, National Yang-Ming Medical University, Taipei, Taiwan; 2Radiology, Taipei City Hospital , Taiwan; 3Radiology, Chang-Hua Christian Hospital, Er-lin branch, Chang-Hua, Taiwan; 4Department of Biomedical Imaging and Radiological Science, National Yang-Ming Medical University, Taipei, Taiwan
Our study was to evaluate ferucarbotran-enhanced MRI with accumulation-phase fat suppression T1-weighted imaging in comparison with gadolinium-enhanced MRI for characterization of T1W hyperintense nodules within cirrhotic liver. In the gadolinium-enhanced group, the MRI sensitivity, specificity and accuracy were 60%, 100% and 73%, respectively. In ferucarbotran-enhanced group, the sensitivity, specificity and accuracy were 100%, 83% and 94%, respectively. The ferucarbotran-enhanced MRI provided additional information of cellular function in differentiation of focal hepatic lesion and ferucarbotran-enhanced MRI is superior to gadolinium-enhanced MRI in characterization of T1W hyperintense nodules. T1W hyperintense nodule depicting hyperintense on ferucarbotran-enhanced accumulation-phase FS-T1WI should be investigated aggressively.