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Abstract #4662

Fast 3D Tracking of 19F Labeled Small Capsules for Combined Morphology and Real-Time Flow Studies in the Gastrointestinal Tract

Tobias Hahn1, Sebastian Kozerke1, Mark Fox2,3, Werner Schwizer2, Andreas Steingoetter, 1,4, Michael Fried2, Peter Boesiger1

1Institute for Biomedical Engineering, University of Zurich and ETH Zurich, Zurich, Switzerland; 2Division of Gastroenterology and Hepatology, University Hospital Zurich; 3Nottingham Digestive Diseases Centre and Biomedical Research Unit Queen's Medical Centre, University Hospital Nottingham; 4Institute of Radiology, Klinikum rechts der Isar, Technische Universitt Mnchen, Munich, Germany.

3D tracking of small-sized 19F labeled capsules is studied using fast modified balanced FFE sequences for concurrent measurements of gastrointestinal function and morphology. Perfluoro-15-crown-5-ether and Hexafluorobenzene are proposed and studied for use as tracking mediums. The proposed imaging protocol is shown to be reliable in tracking small capsules through realistic abdominal phantoms and might therefore bear potential of being a valuable tool in detecting abnormal gastric function and at the same time posing the basis for creating a 3D anatomical model of the complex bowel geometry.