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Abstract #4671

Differentiation of Benign and Malignant Uterine Corpus Tumors: Value of 1H-MR Spectroscopy at 3T

Mayumi Takeuchi1, Kenji Matsuzaki1, Masafumi Harada1, Hiromu Nishitani1

1Department of Radiology, University of Tokushima, Tokushima, Japan

We evaluated 32 uterine corpus tumors (14 malignant including 11 endometrial carcinomas and 3 myometrial tumors; 18 benign including 5 endometrial and 13 myometrial masses) by 1H-MR spectroscopy at 3T. Choline peaks were observed in all 32 lesions, and tended to show higher peaks in malignant tumors. The choline concentration in malignancy (8.77+/-1.91 mM) was significantly higher than that in benign lesions (4.82+/-2.23 mM) (p<0.0001). Using a cut off value of 7.00 mM for malignant lesions had a sensitivity of 93%, specificity of 83%, PPV of 94%, and NPV of 81%.