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Abstract #4732

Reproducibility Evaluation of Spatially Resolved Liver 31P Metabolism Using a Dual Tuned 8-Channel 31P/1H Coil

Anshuman Panda1,2, Scott Ray Jones1,2, Ulrike Dydak1,2

1School of Health Sciences, Purdue University, West Lafayette, IN, United States; 2Department of Radiology and Imaging Sciences, Indiana University School of Medicine, Indianapolis, IN, United States

Regional changes in the 31P metabolite concentration of the whole liver can be acquired using a multi-channel phased-array 31P coil. However, changes in coil placement, separation between anterior and posterior coil, and spectroscopic imaging setup can significantly affect the reproducibility of the data. Methods to maximize data reproducibility including reproducible coil placement and spectroscopic planning, correction of coil sensitivities, and evaluation of the data variability from one scan to another for a whole liver 31P 2D MRSI experiment is presented for a dual tuned 8-channel 31P/1H coil.