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Abstract #4738

Carr-Purcell-Meibom-Gill T2 Mapping of Prostate at 3 T.

Giulio Gambarota1, R L. Janiczek1, Robert V. Mulkern2, Rex D. Newbould1, Brandon Whitcher1

1GlaxoSmithKline Clinical Imaging Center, London, United Kingdom; 2Radiology, Children's Hospital Boston, Boston, United States

In clinical MR examinations of the prostate, a multiparametric approach (T1- and T2-weighted images, quantitative measurement of the apparent diffusion coefficient (ADC) of water, dynamic contrast-enhanced MRI) is becoming standard procedure. The Carr-Purcell-Meiboom-Gill (CPMG) approach has recently been proposed for T2 mapping of the prostate at 1.5 T. No such studies have been performed at 3 T. Translating the CPMG sequence to 3 T is not straightforward and involves compromises in clinical implementation. Here we have shown high quality measurements of T2 may be obtained over the entire prostate by careful design of the clinical acquisition.