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Abstract #4759

Dynamic Contrast-Enhanced MRI of Primary Rectal Cancer at 3T: Correlation with Positron Emission Tomography

Jing Gu1, Pek-lan Khong1, Silun Wang1, Queenie Chan2, Wailun LAW3, Rico Kingyin Liu3, Jingbo Zhang1

1Diagnostic Radiology, The University of Hong Kong, Hong Kong, Hong Kong; 2Philips Healthcare, Philips Electronics Hong Kong Limited, Hong Kong, Hong Kong; 3Division of Colorectal Surgery, The University of Hong Kong, Hong Kong, Hong Kong

We aim to assess the correlations between parameters measured on DCE-MRI and 18F-FDG PET in rectal cancer. We found positive correlations between kep measured by DCE-MRI and SUV values measured by PET/CT. Our findings may indicate that kep during contrast washout phase is better associated with tumor metabolism than Ktrans which is influenced by multiple factors during contrast uptake phase. kep may have the potential as a useful biomarker to reflect biological characteristics of rectum cancer