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Abstract #4796

1H HRMAS NMR Based Metabolomics of Benign and Malignant Neuro-Endocrine Tumors and Its Comparision with Oral Cancer and Benign Gall Bladder Tissues

Shatakshi Srivastava1, Raja Roy1

1CBMR, Centre of Biomedical Magnetic Resonance, Lucknow, Uttar Pradesh, India

A comprehensive metabolic profiling of malignant and non-malignant tumors of neuro-endocrine system alongwith tumors present in other parts of body has been performed using 1H HRMAS NMR spectroscopy. The contributions of small metabolites in each kind of tumor define the mechanisms, which are critical to cellular function of a particular tissue. This may provide a better understanding of biochemical alterations in each tissue and thus, may open novel avenues of therapeutic interventions for various cancers.