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Abstract #4850

Efficient Non-Contrast-Enhanced MRA with Inflow Inversion Recovery by Skipped Phase Encoding and Edge Deghosting (SPEED)

Zheng Chang1, Qing-San Xiang2,3, Hao Shen4, Fang-Fang Yin1

1Department of Radiation Oncology, Duke University, Durham, NC, United States; 2Department of Physics and Astronomy, University of British Columbia, Vancouver, bc, Canada; 3Department of Radiology, University of British Columbia, Vancouver, BC, Canada; 4Applied Science Laboratory, GE Healthcare, Beijing, China

Skipped Phase Encoding and Edge Deghosting (SPEED) has been demonstrated effective in accelerating typical MRI. In this work, SPEED is further developed to achieve higher efficiency in accelerating non-contrast-enhanced MRA with inflow inversion recovery (IFIR). IFIR employs an inversion recovery pulse to suppress signals from static tissue, while leaving inflow arterial blood unaffected, resulting in visible vasculature on modest tissue background. By taking advantages of sparsity of vasculature, SPEED with a single-layer-model can achieve higher efficiency than that achievable with a double-layer-model. The technique is demonstrated with a 3D renal IFIR study achieving undersmapling factors up to 5.