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Abstract #4876

Accelerated Serial MR Imaging in Multiple Sclerosis Using Baseline Scan Information

Alexey A. Samsonov1, Julia V. Velikina2, John O. Fleming3, Mark L. Schiebler1, Aaron S. Field1

1Department of Radiology, University of Wisconsin, Madison, WI, United States; 2Department of Medical Physics, University of Wisconsin, Madison, WI, United States; 3Department of Neurology, University of Wisconsin, Madison, WI, United States


In this work, we present a method to accelerate MS imaging in longitudinal studies through acquisition of fully sampled images at the baseline scan and accelerated undersampled data at follow-ups. W investigated feasibility to accelerate serial scanning of MS patients with 3D pulse sequences (T2 FLAIR and T1 weighted after Gd administration). Our results indicate that the proposed technique has a potential to produce high-quality images from significantly accelerated reduced follow-up acquisition (up to 8 times) and correctly depict T2 and Gd+ lesion load and anatomical content.