Josiane Yankam Njiwa1, Christof Baltes1, Markus Rudin1,2
1ETH-University Zurich, Institute for Biomedical Engineering, Zurich, Switzerland; 2University Zurich, Institute of Pharmacology & Toxicology, Zurich, Switzerland
Dynamic susceptibility (DSC) MRI is increasingly being used to evaluate cerebral microcirculation. In this study is proposed an acquisition scheme, combining partial k-space sampling and pMRI, allowing higher gains for DSC perfusion measurements in small animals. Three male Lewis rats were imaged and a T2*- weighted FLASH sequence was performed for data acquisition. The results show that the used method satisfactory reconstruct DSC-MRI while preserving a good reconstruction quality and image characteristics compared to the non-accelerated and SENSE reconstructed image series. The combination of an Analytic Image based reconstruction with SENSE to reconstruct the images series increase the temporal resolution.