Josiane Yankam Njiwa1, Christof Baltes1,
Markus Rudin1,2
1ETH-University Zurich, Institute for
Biomedical Engineering, Zurich, Switzerland; 2University Zurich,
Institute of Pharmacology & Toxicology, Zurich, Switzerland
Dynamic
susceptibility (DSC) MRI is increasingly being used to evaluate cerebral
microcirculation. In this study is proposed an acquisition scheme, combining
partial k-space sampling and pMRI, allowing higher gains for DSC perfusion
measurements in small animals. Three male Lewis rats were imaged and a T2*-
weighted FLASH sequence was performed for data acquisition. The results show
that the used method satisfactory reconstruct DSC-MRI while preserving a good
reconstruction quality and image characteristics compared to the
non-accelerated and SENSE reconstructed image series. The combination of an
Analytic Image based reconstruction with SENSE to reconstruct the images
series increase the temporal resolution.
Keywords