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Abstract #4966

Anisotropic Twisted Projection Sodium MRI of Articular Cartilage in the Human Knee

Alexander Watts1, Robert Stobbe1, Christian Beaulieu1

1Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada

3D projection imaging has potential benefits in sodium MRI due to ultra-low echo times, but the spherical sampling of k-space leads to isotropic voxels which may not be ideal for imaging thin structures such as cartilage in the knee. Oblate-spheroidal twisted projection imaging, which yields anisotropic voxels, was compared to isotropic acquisition; both projection acquisitions had equal voxel volume (2.56 mm3), twist, readout length, and scan time. The anisotropic projection acquisition had better effective in-plane resolution in a saline resolution phantom and yielded sharper, higher quality sagittal sodium images of human knee cartilage (n=3) in 9 min at 4.7T.