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Abstract #5064

Using PLACE for EPI Distortion Correction of Diffusion Weighted Images (DWIs)

Sofia Chavez1, Elizabeth Ramsay1, Donald Plewes1,2, Greg Stanisz1,2, Q-San Xiang3

1Imaging Research, Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada; 2Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; 3Department of Radiology, University of British Columbia, Vancouver, B.C., Canada

A feasibility study for the application of PLACE, an EPI distortion correction, to diffusion weighted images (DWIs) is presented. PLACE requires a minimum of two input images which differ by an extra blip along the phase encode (PE) direction. The phase relation between the images encodes the PE coordinate, allowing for correction of the EPI-based distortion along the PE direction. Results show successful distortion correction for DWIs of a phantom despite the lower SNR, partial k-space and ramp sampling typical of standard DWI sequences. In vivo application of PLACE to DWI is currently under investigation.