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Abstract #5075

On Accelerated Dynamic Contrast-Enhanced Lung Perfusion Using K-T BLAST

Jia-Shuo Hsu1, Shang-Yueh Tsai2, Yi-Ru Lin3, Hsiao-Wen Chung1

1Institute of Biomedical Electronics and BioInformatics, National Taiwan University, Taipei, Taiwan; 2Dept. of Electrical Engineering, Chang-Gung University, Taoyuan, Taiwan; 3Dept. of Electronic Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan

k-t BLAST accelerates dynamic contrast-enhanced lung imaging with only limited penalty in RMS error. Yet its restrictions including initial-overshooting and temporal-smoothing cast uncertainties on perfusion quantifications and corresponding studies. This work shows that while those restrictions influence intensity estimation on patient images as predicted, little impact is inflicted on the corresponding perfusion quantification, suggesting feasibility of accelerated lung images in clinical studies.