Anup Singh1, Mohammad Haris1, Kejia Cai1, Ari Borthakur1, Hari Hariharan1, Ravinder Reddy1
1CMROI, Department of Radiology, University of Pennsylvania, Philadelphia, PA, United States
De-scalping the brain data is a very critical step in MRI data post-processing and analyzing. Many applications related to brain MRI either require, or benefits from the ability to accurately segment brain from the non-brain tissue. Here we present a simple, fast and robust technique for brain de-scalping. Current de-scalping procedure utilizes lipid ratio map obtained from MRI images without and with lipid saturation pulse, which are normally acquired at clinical scanners. MRI whole brain data from different clinical scanners was successfully de-scalped using current procedure.