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Abstract #5121

Simultaneous δR1 and δR2* Quantification in 5s to Monitor Blood and Tissue Oxygenation with Dynamic (C)O2 Enhanced MRI

Stefanie Remmele1, Tobias Voigt2, Jochen Keupp1, Christian Stehning1, Julien Sngas1

1Philips Research Europe, Hamburg, Germany; 2University of Karlsruhe, Karlsruhe, Germany

This work presents an approach to simultaneous and dynamic dR1, dR2* estimation that combines the beneficial features of currently used techniques for dynamic R1 quantification in DCE-MRI and for dynamic R2*-quantification in D(C)O2E-MRI. The technique aims at increasing the specificity of R2* BOLD imaging during respiratory challenges. Its accuracy and sensitivity is evaluated in phantom and breathold experiments.