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Abstract #0171

Benefits of Optical Prospective Motion Correction for Single-Shot DTI

Murat Aksoy1, Christoph Forman2, Daniel Kopeinigg1, Matus Straka1, Rafael O'Halloran1, Samantha Holdsworth1, Stefan Skare1,3, Roland Bammer1

1Radiology, Stanford University, Stanford, CA, USA; 2Computer Science, Friedrich-Alexander-University Erlangen-Nuremberg, Erlangen, Germany; 3Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden

Correction of motion is important in diffusion tensor imaging (DTI) due to long acquisition times and the increased likelihood of involuntary motion. Single-shot echo-planar imaging (sshEPI), which is the most frequently used sequence in DTI, allows retrospective motion correction that includes realigning individual diffusion-weighted volumes. However, this correction method is considerably flawed due to its inability to deal with intra-volume motion or spin history effects. In this study, we used a monovision-based optical tracking system to provide real-time motion correction capabilities for sshEPI-DTI. In-vivo results demonstrate that even for single-shot methods, prospective motion correction yields more accurate and precise FA maps and fiber tracts than retrospective motion correction.