Alexandru Vlad Avram1, 2, Trong-Kha Truong2, Arnaud Guidon1, 2, Chunlei Liu2, Allen W. Song2
1Biomedical Engineering Department, Duke University, Durham, NC, USA; 2Brain Imaging & Analysis Center, Duke University Medical Center, Durham, NC, USA
We present a novel stimulated echo (STE) based Diffusion Tensor Imaging (DTI) spiral sequence with inherent capability to correct for off-resonance effects (blurring) due to spatial and temporal variations in the main field B0 (e.g. due to tissue susceptibility, eddy currents, system instabilities, etc). Combined with the self-navigated interleaved spiral acquisition (SNAILS) this technique provides dynamic and non-linear corrections for phase errors (e.g. due to motion) and off-resonance effects, which may find broad applications in diffusion weighted MRI where both of these artifacts are significant.