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Abstract #0259

Association of the Apparent Diffusion Coefficient of Bladder Cancer with Metastatic Disease: Preliminary Results

Thais C. Mussi1, Bradley Spieler1, Andrew B. Rosenkrantz1

1Radiology, NYU Langone Medical Center, New York, USA

19 patients with urothelial carcinoma of the bladder who underwent MRI including DWI at 1.5T were included. Among these, 8 had nodal or distant metastatic disease, and 11 had an absence of metastatic disease (mean follow-up 434 days). ADC was measured for each lesion and was significantly lower among those cases with metastatic disease (p=0.0012). Using ADC for prediction of metastatic disease, ROC analysis identified an AUC of 0.920, sensitivity of 87.5%, specificity of 100%, PPV of 100%, and NPV of 91.7%.