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Abstract #0282

Sequence Timing Optimization in Multi-Slice Diffusion Tensor Imaging of the Beating Heart

Christian Torben Stoeck1, Nicolas Toussaint2, Peter Boesiger1, Philip G. Batchelor2, Sebastian Kozerke1,2

1Institute for Biomedical Engineering, University & ETH Zurich, Zurich, Switzerland; 2Imaging Sciences, King's College London, London, United Kingdom

Cardiac DTI faces major challenges due to underlying physiological motion such as breathing and the heart beat. Therefore the timing of diffusion encoding is essential for the success of diffusion weighted imaging in the heart. In this Study we introduce a dynamic timing scout sequence and investigate time windows during the cardiac cycle usable for DTI. Imaging is possible during the upslope of circumferential contraction and symmetry point of rotational motion. It appears that the optimal timing window is independent of the subjects heart rate.