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Abstract #0301

Quantification of Cerebellar Blood Flow using Arterial Spin Labeling

Alan Jerry Huang1,2, Jun Hua1, Jonathan Farrell1, Qin Qin1, James J. Pekar1, Matthias van Osch3, John E. Desmond4, Peter van Zijl

1FM Kirby Research Center, Johns Hopkins University, Baltimore, MD, USA; 2Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, USA; 3Department of Radiology, Leiden University Medical Center, Leiden, Netherlands; 4Department of Neurology, Johns Hopkins University, Baltimore, MD, USA

The cerebellum is an important part of the brain responsible for motor functions, sensory control, and cognitive function. Arterial spin labeling (ASL) is a non-invasive, non-ionizing technique that allows for repetitive measurements of perfusion. The location of the cerebellum allows for access of labeled spins to reach the cerebellum quickly allowing for higher temporal resolution of ASL scans. We report an average cerebellar gray matter perfusion value of 63.65.0 mL/100 g parenchyma/min for three healthy subjects.