Abstract #0360

Time-Resolved Angiography with a Highly Undersampled Multi-Echo 3D Radial Trajectory

Gregory R. Lee¹, Nicole Seiberlich¹, Jeffrey L. Sunshine^1,2, Timothy J. Carroll^3,4, Mark A. Griswold^1,5

¹Radiology, Case Western Reserve University, Cleveland, OH, USA; ²Radiology, University Hospitals Case Medical Center, Cleveland, OH, USA; ³Radiology, Northwestern University, Chicago, IL, USA; ⁴Biomedical Engineering, Northwestern University, Chicago, IL, USA; ⁵Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA

3D Time-Resolved angiography remains challenging due to the high spatial and temporal resolutions required. In the present work, a multishot 3D radial VIPR acquisition with multi-echo readout and pseudorandom undersampling is combined with the recently developed GraDeS reconstruction algorithm. GraDeS allows the reconstruction of sparse images from highly undersampled data. A B0 fieldmap for correction of susceptibility artifact was derived from the same dataset. The resulting angiograms demonstrate clear arterial and venous separation. 1 mm^3 isotropic resolution is achieved at acceleration factors of 100-400 (1.1 s / 0.27s per frame) without the use of view sharing or a composite image.