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Abstract #0364

Superselective MR-Angiography Based On Pseudo-Continuous Arterial Spin Labeling & First Applications in AVM Patients

Michael Helle1, Susanne Rfer1, Wouter Teeuwisse2, Olav Jansen1, David Gordon Norris3,4, Matthias van Osch2

1Institute for Neuroradiology, Christian-Albrechts-Universitt, UK-SH, Kiel, Germany; 2C. J. Gorter Center for High Field MRI, Department of Radiology, Leiden University Medical Center, Leiden, Netherlands; 3Donders Institute for Brain, Cognition & Behaviour, Radboud University Nijmegen, Nijmegen, Netherlands; 4Erwin L. Hahn Institute for Magnetic Resonance Imaging, Essen, Germany

Intra-arterial digital subtraction angiography (DSA) is considered the gold-standard for cerebral angiography but the procedure is invasive and bears the risk of severe complications. Existing MR angiography techniques offer non-invasive approaches but the selectivity is restricted to major brain feeding vessels. In this study, we combined superselective arterial spin labeling with an optimized image acquisition which was applied in healthy volunteers as well as in patients suffering from arterio-venous-malformation (AVM). This approach for selective ASL angiography not only mimics DSA but also combines advantages of superselective labeling and high-resolution 3D image acquisition in a complete non-invasive way.